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Description
Catalogue Number	106432
Synonyms	Trisodium Citrate, Sodium Citrate, Dihydrate

Physicochemical Information
Melting Point	300 °C (anhydrous substance)
pH value	7.5 – 9.0 (50 g/l, H₂O, 25 °C)
Bulk density	600 kg/m3
Solubility	720 g/l

Toxicological Information
LD 50 oral	LD50 Rat > 8000 mg/kg

Safety Information according to GHS
Storage class	10 – 13 Other liquids and solids
WGK	WGK 1 slightly hazardous to water
Disposal	3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.

Storage and Shipping Information
Storage	Store at +2°C to +30°C.

Transport Information
Declaration (railroad and road) ADR, RID	Kein Gefahrgut
Declaration (transport by air) IATA-DGR	No Dangerous Good
Declaration (transport by sea) IMDG-Code	No Dangerous Good

Specifications
Assay (Perchloric acid titration, calc. on anhydrous substance (Ph Eur))	99.0 – 101.0 %
Assay (Perchloric acid titration, previously dried substance) (JP/USP)	99.0 – 100.5 %
Identity (Na)	passes test
Identity (Citrate)	passes test
Identity (reaction upon ignition)	passes test
Appearance	white to almost white crystals
Appearance of solution (100 g/l, CO₂-free water)	clear and colorless
Acidity or alkalinity	passes test
pH (50 g/l CO₂-free water)	7.5 – 8.5
Chloride (Cl)	≤ 50 ppm
Sulfate (SO₄)	≤ 150 ppm
Al (Aluminium)	≤ 5 ppm
As (Arsenic)	≤ 1 ppm
Hg (Mercury)	≤ 1 ppm
Pb (Lead)	≤ 1 ppm
Oxalate (as C₂H₂O₄)	≤ 100 ppm
Tartrate (C₄H₄O₆)	passes test
Residual solvents (ICH (Q3C))	excluded by manufacturing process
Readily carbonisable substance	passes test
Water (according to Karl Fischer)	11.0 – 13.0 %
Loss on drying (180 °C, 18 h)	10.0 – 13.0 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., BP, JP, USP, E 331 Conforms to the purity criteria on food additives according to the current European Commission Regulation.
Corresponds to Ph. Eur., BP, JP, USP, E 331 Conforms to the purity criteria on food additives according to the current European Commission Regulation.

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