Açıklama

Description
Catalogue Number	111609
Synonyms	Embedding agents for microscopy, Embedding agent, Histosec®
Description	Histosec™ pastilles
Overview	Histosec™ pastilles – solidification point 56-58 °C embedding agent for histology, is an embedding medium for histology of samples of human origin. it is a paraffin enriched with polymers and containing DMSO (dimethyl sulfoxide). Histosec™ pastilles (without DMSO) (Cat. nr. 115161) is also available. DMSO (dimethyl sulfoxide) increases the rate of penetration of paraffin and provides additional preservation of the tissue structures. Its melting range is between 56 – 58 °C and, within this range any specimen can be processed without fear of damage irrespective of the method used. In most clinical laboratories the paraffinization is performed with an automated embedding system and is performed directly after the histoprocessing. The Histosec™ pastilles are well soluble with the Intermedia Xylene (isometic mixture) (Cat .no. 108298) or xylene substitutes such as Neo-Clear™ (Cat. no 109843).The paraffin is an IVD registered product and CE certified, thus can be used for clinical diagnostic purposes. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

Product Information
HS Code	2712 20 00
Quality Level	MQ400

Applications
Application	solidification point 56-58°C embedding agent for histology

Physicochemical Information
Flash point	>100 °C
Bulk density	400 kg/m3

Toxicological Information
LD 50 dermal	LD50 Rabbit > 3000 mg/kg

Safety Information according to GHS
Storage class	10 – 13 Other liquids and solids
WGK	WGK 2 obviously hazardous to water
Disposal	3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.

Storage and Shipping Information
Storage	Store at +15°C to +25°C.

Specifications
Solidification point (rotating thermometer method)	56 – 58 °C
Effect of heating (at 60 °C/100 g)	clear melt within max. 20 hours
Solubility in xylene (at 20 °C/0.1 g in 5 ml)	clear solute within max. 20 hours
Cutting results (4 µm slices)	conforms
Solubility of slices in xylene	< 50 seconds

Merck 111609 2504 Histosec Pastiles (56-58 C) Boncuk Paraffin 2,5 KG.